ea0094p276 | RET | SFEBES2023
Boon Oh Han
, Abdel-Aziz Tarek
, Brain Caroline
, Rozalen Garcia Virginia
, Butler Colin
, Stoneham Sara
, R Kurzawinski Tom
Introduction: Pathogenic RET mutations cause Multiple Endocrine Neoplasia type 2 (MEN2) and sixty-one have been classified according to their penetrance of MTC. However, this distinct pattern of genotype-phenotype presentations is not always precisely predictable. P.Val804Met, the most frequent mutation in RET, is currently thought to confer a low lifetime risk with later onset of MTC.Methodology: We present demographica...